SAN DIEGO (AP) — Fernando Tatis Jr. homered twice and scored the go-ahead run on a wild pitch as the San Diego Padres improved to 11-0 at home by beating the Chicago Cubs 10-4 on Monday night in the opener of a three-game series between National League division leaders.

The Padres have the best record in the majors at 14-3.

Tatis hit a solo homer with two outs in the third inning, scored the tiebreaking run on a wild pitch in a three-run seventh and then hit a two-run shot in the eighth. He has six home runs overall — tying seven other players for the big league lead — and five in his last six games. It was his 12th career multi-homer game.

Luis Arraez also homered in the eighth, his second, to give the Padres their first back-to-back homers this season.

The Cubs took a 3-1 lead in the fourth. Michael Busch hit a two-run homer off Dylan Cease, his fourth, after Justin Turner reached on a fielding error by third baseman Manny Machado. Nico Hoerner and Pete Crow-Armstrong hit consecutive doubles with one out.

Tatis homers twice as Padres beat Cubs 10-4 to improve to 11-0 at home | iNFOnews.ca — San Diego Padres’ Fernando Tatis Jr. (23) is hit with a pitch during the seventh inning of a baseball game against the Chicago Cubs, Monday, April 14, 2025, in San Diego, Calif. (AP Photo/Denis Poroy)

Busch’s homer ended a 37-inning scoreless streak by San Diego’s pitching staff, dating to the third inning Wednesday at the Athletics. The Padres shut out the Colorado Rockies in a three-game weekend series.

The Padres tied it in the sixth and then went ahead in the seventh. Tatis drew a leadoff walk, advanced on Arraez’s double and, after Machado was intentionally walked, raced home on a wild pitch by Nate Pearson (0-1) for a 4-3 lead. Gavin Sheets then hit a two-run single.

Adrian Morejon (1-0) got the win.